At Friday’s “Marvel’s Next Big Thing” panel at San Diego Comic-Con, the publisher revealed an upcoming limited series featuring an epic crossover: Predator Vs. Punisher.
Written by Frank Tieri with art by Jesús Saíz, Predator Vs. Punisher will be a four-issue arc debuting in November. But they aren’t the only killers in this comic—plenty of Marvel villains will appear in this explosive arc.
Here’s the synopsis:
THE PUNISHER TAKES ON THE PREDATOR!
New York City becomes a hunting ground when a Predator arrives looking for worthy prey and finds Frank Castle! As crime bosses fall, the body count rises and the streets run red, two legendary killers violently collide in a brutal showdown featuring a murderer’s row of underworld villains including KINGPIN, JIGSAW, SILVERMANE, THE OWL and more!
“This is the series that’ll answer the age old question of who is pop culture’s greatest killing machine,” Tieri teased. “Now, fans know I’ve written the Punisher before—in everything from Punisher Noir to the legendary Space: Punisher—but this is the first time I’m actually tackling the Predator. And as a teen who was front row glued to his seat in the theaters as Arnold yelled ‘Get to the Choppa!’ pitting these two against each other is especially a thrill for me.
“Our story sees the Predator instigating a mob war between some of Marvel’s biggest gangland characters—but the thing is, we’ll quickly realize the mob might not be his only target… but rather a certain vigilante with a skull on his chest, as well,” he continued. “Fans can expect—SPOILER ALERT—a $%^& ton of blood and violence, but also a lot of twists and turns… including an unexpected shared past between our two combatants. ‘If it bleeds we can kill it.’ The only question will be… who is it that ends up getting killed?”
“Seeing two iconic killers test each other in ways neither expects is a guilty joy,” added editor Mark Paniccia. “Frank Tieri and Jesús Saíz are the perfect choice to deliver a showdown this ruthless, visceral, and unforgettable. They’ve created an instant classic!”
Predator Vs. Punisher #1 will feature main cover art by Dustin Weaver, a variant by Alex Maleev, and an homage variant inspired by Frank Castle’s first appearance in The Amazing Spider-Man #129 by Leinil Francis Yu. Check out the two variant covers below, as well as promotional artwork by Weaver.




Predator Vs. Punisher #1 will be available digitally and at your local comic shop in November.
Stay tuned to The Beat for more news from SDCC ’26.











